个人简介
雷蕾
博士，副教授，硕士生导师
2019- 今 ，yl6809永利官网生命科学与医学部 副教授
2013-2019 yl6809永利官网生命科学与医学部 讲师
2009-2013 北京大学 基础yl6809永利官网 神经生物学系 理学博士
2004-2009 北京大学 基础yl6809永利官网 医学学士
主要研究方向：研究食物及环境因素对结直肠癌发生发展的影响。通过研究结直肠癌发病的分子机制寻找遗传标志物，为结直肠癌的早期筛查，精准治疗和预后诊断奠定基础。
承担的科研项目
2019 陕西省科技厅青年项目（2019JQ-538）
2018 西部资源生物与现代生物技术教育部重点实验室开放基金
2018 陕西省教育厅青年项目（18JK0796）
2015 国家自然科学基金青年基金项目（31401081）
主要研究成果
(1) Lei Lei; Jun Yang; Jianan Zhang; Guodong Zhang*; The lipid peroxidation product EKODE exacerbates colonic inammation and colon tumorigenesis, Redox Biology, 2021, 101880: 2213-2317
(2) Shuzhen Liu; Qing Cao; Guoyan An; Bianbian Yan; Lei Lei*; Identification of the 3-lncRNA Signature as a Prognostic Biomarker for Colorectal Cancer, International Journal of Molecular Sciences, 2020, 2020(21): 0-9359
(3) Lei Lei*; Guoyan An; Ziqing Zhu; Shuzhen Liu; Yutong Fu; Xiaonan Zeng; Qing Cao; Bianbian Yan; C8orf48 inhibits the tumorigenesis of colorectal cancer by regulating the MAPK signaling pathway, Life Sciences, 2020, 266(2021): 0-118872.
(4) Qing Cao#; Zewen Dong#; Shuzhen Liu; Guoyan An; Bianbian Yan; Lei Lei*; Construction of a metastasis-associated ceRNA network reveals a prognostic signature in lung cancer; Cancer Cell Int (2020) 20:208
(5) Lei Lei; Xiaojuan Zhao; Shuzhen Liu; Qing Cao; Bianbian Yan; Jin Yang*; MicroRNA-3607 inhibits the tumorigenesis of colorectal cancer by targeting DDI2 and regulating the DNA damage repair pathway, Apoptosis, 2019,24(7-8): 662-672.
(6) Hongjuan He; Xiaojuan Zhao; Ziqing Zhu; Le Du; Erfei Chen; Shuzhen Liu; Qiqi Li; Jing Dong; Jin Yang; Lei Lei*; MicroRNA-3191 promotes migration and invasion by downregulating TGFBR2 in colorectal cancer, Journal of Biochemical and Molecular Toxicology, 2019, 33(6): 0-e22308.
(7) Hongjuan He #; Lei Lei#; Chen Erfei; Xu Xiaona; Wang Lili; Pan Junqiang; Yang Fangfang; Wang Min; Dong Jing; Yang Jin*; The screening of the functional microRNA binding site SNPs in sporadic colorectal cancer genes, Cancer Biology and Therapy, 2017, 18(6): 407-413.
(8) Lei Lei; Yang Ying; He Hongjuan; Chen Erfei; Du Le; Dong Jing; Yang Jin*; Flavan-3-ols consumption and cancer risk: A meta-analysis of epidemiologic studies, Oncotarget, 2016, 7(45): 73573-73592.
